The Psychopharmacology laboratory has a wide range of facilities for conducting behavioural, neurochemical and immunohistochemical research with rodents.

Basic infrastructure

  • Rodent breeding facilities
  • Colony for holding up to 1200 rats
  • Mouse facilities to be added in near future
  • American optical cryostat
  • Olympus BX-40 microscope
  • Polaroid DCM Microscope camera
  • Gillson peristaltic perfusion pump
  • Small animal surgery
  • -80°C freezer
  • National Instruments Labview and Strawberry Tree automation and data acquisition
  • Extensive collection of Mac and PC computers for data collection and analysis

Facilities for behavioural testing

  • Social interaction test (with automated video analysis)
  • Elevated Plus maze
  • Emergence test
  • Cat odour avoidance test
  • Ultrasonic vocalization measurement, analysis and playback
  • Object recognition test (with automated video analysis)
  • Radial arm maze
  • Olfactometers for assessing olfactory discrimination, olfactory learning and olfactory memory
  • Intravenous drug self-administration chambers
  • Locomotor activity testing chambers (automated video tracking)
  • Conditioned place preference
  • Intracranial self-stimulation
  • Operant chambers

Physiological testing

  • Datasciences International telemetry system for body temperature and cardiovascaular measurements

Neurochemistry

  • Shimadzu HPLC system with refrigerated autosampler and eletrochemical and UV detection
  • Receptor binding assays performed in conjunction with Department of Pharmacology
  • Quantitative autoradiography performed in conjunction with Andy Lawrence (Florey Institute, Melbourne)

Immunohistochemistry

  • Facilities for c-fos immunohistochemistry
  • Labview image analysis system
  • Plate Reader
  • GCMS

Proteomics and Peptodomics Facilities

  • Liquid chromatography
  • Protein and peptide purification
  • 1D and 2D gel electrophoresis
  • Gel imaging and analysis
  • MALDI-TOF peptide mass fingerprint (PMF)
  • Protein identification (Protein ID)
  • Phosphopeptide mapping (TiO2IMAC, LC-MS/MS approaches)
  • Biomarker discovery
  • Western blotting